https://doi.org/10.25678/0007HK

Data for : Demographic fluctuations and selection during host-parasite coevolution interactively increase genetic diversity

Host-parasite interactions can cause strong demographic fluctuations accompanied by selective sweeps of resistance/infectivity alleles. Both demographic bottlenecks and frequent sweeps are expected to reduce the amount of segregating genetic variation and therefore might constrain adaption adaptation during coevolution. Recent studies, however, suggest that the interaction of demographic and selective processes is a key component of coevolutionary dynamics and may rather positively affect levels of genetic diversity available for adaptation. Here, we provide direct experimental testing of this hypothesis by disentangling the effect of demography, selection, and of their interaction in an experimental host-parasite system. We grew 12 populations of a unicellular, asexually reproducing algae (Chlorella variabilis) that experienced either growth followed by constant population sizes (3 populations), demographic fluctuations (3 populations), selection induced by exposure to a virus (3 populations), or demographic fluctuations together with virus-induced selection (3 populations). After 50 days (approximately 50 generations), we conducted whole-genome sequencing of each algal host population. We observed more genetic diversity in populations that jointly experienced selection and demographic fluctuations than in populations where these processes were experimentally separated. In addition, in those 3 populations that jointly experienced selection and demographic fluctuations, experimentally measured diversity exceeds expected values of diversity that account for the cultures’ population sizes. Our results suggest that eco-evolutionary feedbacks can positively affect genetic diversity and provide the necessary empirical measures to guide further improvements of theoretical models of adaptation during host-parasite coevolution.

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Le Pennec, G., Retel, C., Kowallik, V., Becks, L., & Feulner, P. (2022). Data for : Demographic fluctuations and selection during host-parasite coevolution interactively increase genetic diversity (Version 1.0) [Data set]. Eawag: Swiss Federal Institute of Aquatic Science and Technology. https://doi.org/10.25678/0007HK

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The associated article

Le Pennec, G., Retel, C., Kowallik, V., Becks, L., & Feulner, P. G. D. (2023). Demographic fluctuations and selection during host‐parasite coevolution interactively increase genetic diversity. Molecular Ecology. https://doi.org/10.1111/mec.16939

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Author	Le Pennec, Guénolé Retel, Cas Kowallik, Vienna Becks, Lutz Feulner, Philine
Keywords	experimental evolution,host-parasite interactions,genetic diversity,demography,selective sweeps
Variables	flow_cytometric_cell_counts growth_rate
Taxa (scientific names)	Chlorella variabilis NC64A Chlorovirus-PBCV1
Organisms (generic terms)	Algae Virus
Systems	lab (chemostats)
Timerange	2018
Geographic Name(s)	Lab-grown algae populations
Review Level	general
Curator	Le Pennec, Guénolé
Contact	Feulner, Philine <philine.feulner@eawag.ch>
DOI	10.25678/0007HK